Jolltrin

Trientine should be taken orally at about the same time each day, on an empty stomach, at least one hour before meals or two hours after meals and at least an hour apart from any kind of other drug, milk or food. Trientine 25 mg capsules should be swallowed whole with water. The capsules should not be broken, opened, or chewed.

Most common adverse reactions include cramps, heartburn, epigastric pain and tenderness, fissuring and flaking of the skin, thickening, hypochromic microcytic anemia, acute gastritis, aphthoid ulcers, melena, anorexia, malaise, abdominal pain, muscle pain, weakness and rhabdomyolysis.

Patients with trientine hydrochloride should be observed closely for signs of possible hypersensitivity.

Patients who are taking trientine should remain under regular medical supervision throughout the period of drug administration.

Patients (especifically women) must be closely observed or monitored for any evidence of iron deficiency anemia.

Tryprine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Care should be exercised in the handling of TRIENTINE. Trientine capsules should not be opened or crushed. Store permitted between 2°-8°C (36°-46°F).