Dobutamine

Dobutamine (dobutrex) basically is a sterile powder which should be dissolved as well as diluted with the suitable sterile fluids. Dobutamine should be given as a slow injection into a vein (continuous infusion or a drip).

Most common adverse reactions include angina, ventricular arrhythmias, increased heart rate, nausea, headache, shortness of breath, hypotension, and increased shunt fraction (pulmonary vasodilation).

Administration of dobutamine injection, may be responsible for causing reactions including skin rash, fever, eosinophilia, and bronchospasm.

Such patients who are with the pre-existing hypertension appear to have a higher risk of developing an exaggerated pressure response.

While administration of dobutamine 250 mg, as with any adrenergic agent, ECG as well as blood pressure must be continuously monitored.

Women with childbearing potential should avoid treatment with dobutamine dosage. In such patients who’ve atrial fibrillation with the rapid ventricular response, a digitalis preparation is used before institution of the dobutamine therapy.

Breastfeeding needs to be interrupted or discontinued for the duration of the dobutamine injection treatment.

Care should be exercised in the handling of Dobutrex. Dobutrex Injections should not be opened or broken. This medication should be kept in the cool dry place where temperature stays below 25°C.