Eltrombopag is an orally bioavailable, small-molecule TPO-receptor agonist that interacts 485 with the transmembrane domain of the human TPO-receptor and initiates signaling cascades that 486 induce proliferation and differentiation from bone marrow progenitor cells.
Treatment of Thrombocytopenia in Patients with Hepatitis C Infection PROMACTA is indicated for the treatment of thrombocytopenia in patients with chronic hepatitis C to allow the initiation and maintenance of interferon-based therapy.
Treatment of Severe Aplastic Anemia PROMACTA is indicated for the treatment of patients with severe aplastic anemia who have had an insufficient response to immunosuppressive therapy.
Therapeutic Category : Thrombocytopenia
CAS Number : 496775-61-2
Molecular Formula : C25H22N4O4
Molecular Weight : 442.5 g/mol
Mesh Size : As per Customer Requirement
Metrochem Development Status : Wishlist