Description
Cuprimine is used to treat rheumatoid arthritis, Wilson's disease (a condition in which high levels of copper in the body cause damage to the liver, brain, and other organs), and a certain disorder which causes kidney stones (cystinuria). For the treatment of rheumatoid arthritis, penicillamine is known as a disease-modifying antirheumatic drug (DMARD). It helps to decrease pain/tenderness/swelling in the joints. For the treatment of Wilson's disease, penicillamine binds to copper and helps it to be removed from the body. Decreasing copper levels helps to improve liver function and the mental/mood/nerve problems (such as confusion, difficulty speaking/walking) caused by the disease. For the treatment of cystinuria, penicillamine helps to decrease the amount of a certain substance (cystine) in the urine which can cause kidney stones.
Take Cuprimine by mouth on an empty stomach (1 hour before or 2 hours after meals) as directed by your doctor. Take Cuprimine at least 1 hour apart from other drugs (especially antacids), milk, or food. Dosage of Cuprimine is based on your medical condition and response to treatment. Use Cuprimine regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Your doctor may also direct you to take vitamin B6 (pyridoxine) and iron. Follow your doctor's instructions carefully. If you need to take iron or other products that contain minerals (such as zinc), take it at least 2 hours before or after taking penicillamine. Consult your doctor before taking any products containing minerals since they may block the absorption of penicillamine. For the treatment of rheumatoid arthritis, it may take 2 to 3 months before you see any improvement in your condition. For the treatment of Wilson's disease, follow the diet recommended by your doctor to get the most benefit from Cuprimine. Your condition may not improve for 1 to 3 months and may actually get worse when you start Cuprimine. Tell your doctor right away if your condition continues to worsen after a month of treatment. For the treatment of cystinuria, follow the diet recommended by your doctor to get the most benefit from Cuprimine. Drink plenty of water unless your doctor directs you otherwise. Tell your doctor if your condition does not improve or if it worsens.
Before taking penicillamine, tell your doctor or pharmacist if you are allergic to it; or to penicillins; or if you have any other allergies. Cuprimine may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using Cuprimine, tell your doctor or pharmacist your medical history,a previous severe reaction to penicillamine (such as aplastic anemia, agranulocytosis), kidney disease, blood/bone marrow disorders (such as thrombocytopenia). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Penicillamine is not recommended for use during pregnancy. It may harm an unborn baby. However, it may sometimes be used during pregnancy in certain situations (such as treating Wilson's disease). Consult your doctor for more details. It is unknown if Cuprimine passes into breast milk. Because of the possible risk to the infant, breast-feeding while using Cuprimine is not recommended. Consult your doctor before breast-feeding.
If you miss a dose of Cuprimine, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
See also How to Use section. The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with Cuprimine. While using Cuprimine, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.digoxin, gold salts (such as auranofin), drugs to treat malaria (such as chloroquine), phenylbutazone, other drugs that decrease bone marrow function (such as azathioprine, cancer chemotherapy, trimethoprim/sulfamethoxazole). This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.
What are Cuprimine side effects?
Side effects are physical, mental or emotional symptoms which occur in addition to or outside of the desired effect of a therapeutic treatment such as an over-the-counter or prescribed drug or medication. Side effects from Cuprimine may occur at the beginning or at the end of treatment and may also depend on the length of time an individual remains on the treatment. Side effects, also known as adverse effects, are generally more likely to occur when starting treatment. Individuals may also experience side effects from Cuprimine as a result of an interaction with other medications.
Side Effects of Cuprimine
The side effects of Cuprimine may vary in number and intensity for many different reasons. Factors such as age, weight, gender and ethnicity may influence the side effects of Cuprimine. Also, an individual’s state of general physical health and seriousness of the disease or illness as well as an increase or decrease in dosage may lead to side effects. Further, side effects from Cuprimine may also occur as a result of an interaction with certain herbal supplements, foods or drinks.
Prescription drug side effects can be serious and may cause patients to stop the treatment. However, when side effects from the use of a prescription drug, such as Cuprimine, do occur a patient should consult their physician. A physician may prescribe an additional treatment in order to control the symptoms or an adjustment in the dosage may be made. In addition, changes to diet, exercise or other lifestyle activities may help to lessen the side effects of Cuprimine.
By understanding side effects and the factors which may influence the occurrence of side effects patients are empowered to take an active role in their care. Patients who have specific questions about the side effects of Cuprimine, or any other medication, should contact their physician. General information about Cuprimine and the side effects associated with Cuprimine are described in the following:
| Common Cuprimine Side Effects | |
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| Less Frequent Cuprimine Side Effects | |
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Severe
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Less Severe |
| Rare or Very Rare Cuprimine Side Effects | |
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Severe
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Less Severe
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Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Cuprimine when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Cuprimine Drug Information
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